Thanks
Pathologist (Immunologist)
Antihistamines are not anti-itch medications, but they can sooth the underlying allergies, which may be associated with the itch. In that way, they can sometimes help to improve the itch. The sedating antihistamines, such as the old-fashioned Phenergan is often used as an anti-itch preparation, but it is very sedating. This is probably the reason why it is effective in reducing the itch.
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