Adverse events following hepatitis B vaccination are uncommon. Soreness at the injection site (5% occurance), fever (usually low grade, 2-3% occurance), and the possibility of nausea, dizziness, malaise, myalgias and athralgias. Fevers can be expected among neonates (0.6-3.7% occurance). Anaphlaxis has been reported very rarely among adults. (source: B Positive - all you wanted to know about hepatitis B: a guide for primary care providers. 2008). These uncommon and relatively minor adverse events need to be weighed against the very real risk of long term hepatitis B health problems - especially in the case of hepatitis B acquired at birth.
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