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Respiratory & Sleep Medicine Physician
Narcolepsy is actually a neurological disorder, rather than a psychological or mental disorder. People with narcolepsy who have symptoms of cataplexy (sudden muscle weakness), have been shown to be missing the neurotransmitter orexin (sometimes called hypocretin). Orexin is very important in maintaining alertness and also in keeping sleep stable. In the absence of orexin, as occurs in narcolepsy, people have trouble both staying awake during the day and staying asleep at night.
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